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KMID : 0363420190330010034
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Journal of Korean Oriental Pediatrics
2019 Volume.33 No. 1 p.34 ~ p.45
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Current Trends and Future Directions of Gut Microbiota and Their-Derived Metabolite Study in the Pediatric Perspective of Korean Medicin
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Ryu Dong-Ryeol
Kim Ki-Bong
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Abstract
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Objectives : The purpose of this study is to highlight recent gut-microbiota studies and to encourage gut-microbiota-related researches in Pediatric science of Korean Medicine.
Methods : We searched gut microbiota related studies and patents via the PubMed database of the US National Institutes of Health (NIH) and the PatentScope database of the UN World Intellectual Property Organization (WIPO) to see current trends of gut microbiota studies.
Results : All searched research and review articles in gut-microbiota studies were analyzed and presented as two charts, showing the recent trends of gut microbiota research. We summarized and discussed the significance of the selected fifty-six articles. Also, we listed reported gut-microbiota-derived small metabolites, impacting on human health and diseases.
Conclusions : This study emphasizes the critical roles of gut-microbiota and their-derived small metabolites in the human physiology and pathology. We know and agree that many natural compounds in Korean Medicine could be converted into small metabolites by gut microbiota in our body. Thus, it is important to encourage physicians and researchers of gut microbiota in the arena of Pediatric Korean Medicine. We believe that researchers will find a lot of unknown metabolites produced by gut microbiota from natural compounds in Korean Medicine.
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KEYWORD
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Gut microbiota, Gut microbiota-derived metabolite, Obesity, Metabolic disorder
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